Vectors derived from human adenovirus type 5, which typically lack the olea europaea montra E1A and E1B genes, induce robust innate immune responses that limit their therapeutic efficacy.We reported previously that the E1B 55 kDa protein inhibits expression of a set of cellular genes that is highly enriched for those associated with anti-viral defe

Improvements in life expectancy have been considerable over the past hundred years.Forecasters have taken to applying historical trends under an assumption of continuing improvements in life expectancy in the future.A read more linear mixed effects model was used to estimate the trends in global and regional rates of improvements in life expectancy

IntroductionSkeletal muscle satellite cells (MuSCs or stem cells) play a crucial role in muscle development, maintenance, and regeneration, supporting both hypertrophy and regenerative myogenesis.Syndecans (SDCs) act as communication bridges within the muscle microenvironment, regulating interactions with extracellular matrix components and contrib

Lysine carbamylation is a non-enzymatic protein post-translational modification (PTM) that plays important roles in regulating enzymatic activity and the pathogenesis of diseases such as atherosclerosis, rheumatoid arthritis, and uremia.The progress of understanding the roles of carbamylation in altitude sunscreen biological systems has been delaye

Abstract Background Euphorbia lathyris L., a Traditional Chinese medicine (TCM), is commonly used for the treatment of hydropsy, ascites, constipation, amenorrhea, and scabies.Semen Euphorbiae Pulveratum, which is another type of Euphorbia lathyris that is commonly used in TCM practice and is obtained by removing the oil from the seed that is calle